The Kansas City Zoo is participating in the first documented health assessment and disease ecology study of the Eastern spotted skunk, a species in decline throughout the Midwest. By supporting this project, the Kansas City Zoo is engaging in direct conservation work with a native and regional species of conservation concern. The population of skunks being assessed inhabit the forested Ozark mountain region spanning southern Missouri and northern Arkansas. This project is important because the reasons for decline of the Eastern spotted skunk in this part of the country are unclear. A major goal of the study is to identify potential health and disease based risk factors that may be associated with other wildlife and/or domestic animals sharing the same environment as the skunks. The data and conclusions drawn from this study will enable the zoo to provide new and necessary information to help support and guide Eastern spotted skunk conservation efforts across the species’ range.